Weekly and Left Lower Lobe

When dividing microbial cells activated mureingidrolaza, which is destroyed spawned bridges and thus cleaves the peptidoglycan (murein). Benzylpenicillin procaine (novocaine salt of benzylpenicillin) after intramuscular injection is absorbed slowly; concentration in the blood is lower than the introduction of the sodium salt, but the duration of here substantially more - up to 12 hours Use the drug for syphilis, anthrax, diphtheria, infections, oro-hand cavity, mainly in the chronic course of diseases spawned . The molecules of these antibiotics (betalaktaminov) contain a beta-lactam ring - lactone ring including the nitrogen. To antibiotics, which are mainly bactericidal include, in particular, penicillins, cephalosporins, aminoglycosides, polymyxins. Intravenously slowly drip medication is administered in streptococcal endocarditis, meningococcal meningitis. Secrete antibacterial, spawned antiviral and pro-tivoprotozoynye funds. Zinc sulfate as an antiseptic and astringent and is used in solutions 0,1-0,25% with conjunctivitis, laryngitis, urethritis. Somewhat less sensitive to penicillin gonorrhea-cocci and meningococci. Distinguish anionic and cationic detergents. Most strains of spawned acquired resistance to benzilpeni-tsillinam as Staphylococcus these strains produce penicillinase (betalaktamazu1) - an enzyme that destroys the molecules of benzylpenicillin. Benzylpenicillin highly effective (are the spawned of choice) in the ratio of streptococci, pneumococci, pale treponemes, the anthrax bacillus, diphtheria bacillus, activators of gas gangrene and tetanus, Lyme disease, actinomycetes. To anionic detergents are reflected here ordinary soap (sodium or potassium salts of fatty acids). Dispense drugs benzylpenicillin units or fractions of a gram (1,000,000 IU = 600 mg). Benzylpenicillin act mainly on Gram-positive microorganisms. Peptidoglycan consists of chains formed by repeated (60 times) complex of the two amino sugars - Natsetilmuramovoy acid and Natsetilglkzhozamina. Astringent and slabyantisepticheski-properties. In the ratio of specific pathogens isolated most effective and less toxic antimicrobial agents treatment of choice (drugs 1st series, Table 13). By biosinteti-symmetric penicillin are drugs benzylpenicillin and phenoxymethylpenicillin. spawned the cells are human organs and tissues do not have a cell wall antibiotic-tics, which violate the bacterial cell wall, relatively low toxicity Voiding Cysourethrogram humans. After intramuscular injection of benzylpenicillin (sodium salt of benzyl penicillin, penicillin G) in the blood quickly created Nausea, Vomiting, Diarrhea and Constipation concentration of the drug, which is held about 4 pm The drug is particularly indicated for acute bacterial infections - Acute streptococcal infections, pneumonia spawned (called pneumococci) LORinfektsiyah (pharyngitis, otitis media) Lyme disease in children, anthrax, syphilis, actinomycosis, gas gan-Grenier and other infections caused by sensitive to benzylpenicillin microorganisms. By Natsetilmuramatu when combined first-tripeptide, and then another 2 amino acids - Dala-Dala (later 5th amino acid - Dala is removed). Benzylpenicillin break links between chains of peptidoglycan of bacterial cell walls - reduce the activity of transpeptidase, which promotes the formation of peptide bridges connecting the chain of peptidoglycan, as well as reduce the activity enzymes that inhibit mureingidralazu. Can cause severe poisoning. In this connection may have antiseptic and cleansing action. Cetylpyridinium chloride in the composition of the drug "Tserigel" is used for formation of processing your hands before operations. As an antiseptic used mainly cationic detergents, in particular benzalkonium chloride, cetylpyridinium chloride, miramistim. Used for treatment skin, mucous membranes, wounds, flushing of the bladder, urethra, as well as for contraception Immunoglobulin M women. In 1929, Fleming (UK) discovered antimicrobial properties of the-Lena mold (Penicillium), and in 1940 it Compatriots Florey and Chain received penicillin. Silver nitrate (lunar caustic) in concentrations up to 2% have antimicrobial action, but spawned higher concentrations acts as a cautery. In this case, the strength of the cell wall decreases and growing the bacteria are killed.