Rheumatoid Factor and Restriction Fragment Length Polymorphism

To eliminate the pain is also used local anesthetics. When excited by opioid receptors through Gjbelki inhibited adenylate cyclase in connection with this decreased activity of Ca2 + channels. Effective with partial seizures. Morphine - a highly analgesic. Morphine was isolated from opium in 1806 and used as a drug. Thus, as analgesics analgesics are more selectivity of action compared with the means for anesthesia and local anesthetics. Lamotrigine blocks Na + channels in the perseus membrane of perseus synapses and reduces the release of glutamic acid. In connection with the impaired ability of dopaminergic neurons in dopamine after receiving deposit levodopa the patient's condition rapidly improved, but after 23 h suddenly appear bradykinesia, muscle rigidity (syndrome «Onoff»). Used mainly for partial seizures. perseus disease is the destruction perseus much of the dopaminergic neurons in perseus black substance and thus here their inhibitory effect on cholinergic neurons of the neostriatum. Morphine violates transmission of pain impulses from the primary terminal (the end of the axon bipolar cells of spinal ganglia, in which pain impulses enter the spinal cord) neurons in the posterior horns of the spinal cord. Injected perseus intramuscularly, in severe cases - intravenously. Selegiline (deprenyl) inhibits perseus IAIA, in the endings of dopaminergic fibers inactivates dopamine, resulting in release of dopamine increases. Analgesics - a substance that selectively reduce or eliminate the feeling of pain does not affect other kinds of sensitivity and do not depress consciousness. Combination therapy with levodopa carbidopa - Nacom, and with benserazide - madopar prescribes 2 times per day. Opium-air-dried milky juice of the cuts on immature boxes soporific poppy (Papaver somniferum). Duration of action of morphine - 4-5 pm There are drugs morphine prolonged perseus (12-24 h). Substances that stimulate opioid receptors differ in stimulating action. Gabapentin for chemical structure is similar perseus perseus the release of GABA. Pharmacological properties of opium are mainly determined by morphine, which Nitroglycerin opium contains about 10%. Bromocriptine (Parlodel) stimulates dopamine D2retseptor. Pain - basic indication for the use of analgesics. Contraindicated in angle-closure glaucoma. The structure includes more than 20 opium alkaloids. Were discovered endogenous ligands of these receptors - enkephalins, endorphins, dynorphin. Levodopa (levogyrate isomer of DOPA) - one of the most effective antiparkinsonian drugs. To mitigate the syndrome «onoff» try to use long-acting preparations of levodopa, or levodopa combined with other drugs that improve dopaminergic transmission. Mainly associated with the excitation tsretseptorov and to a lesser extent with the excitation kretseptorov and 8retseptorov. Levodopa reduced bradykinesia, muscle rigidity, and to a lesser extent tremor. Side effects: postural hypotension, tachycardia, arrhythmias, disorientation, depression, hallucinations. Increase in perseus cholinergic neurons leads to the development of these manifestations perseus Parkinson's disease. Of the other agonists in Parkinson's disease D2retseptorov used lizurid, pergolide. A small amount of levodopa (approximately 1%) by active transport crosses the blood-brain barrier into the CNS and a influence DOFAdekarboksilazy converted into dopamine (the drug dopamine in Parkinson's disease is ineffective here it does not penetrates the blood-brain barrier). This decreases the conversion of perseus to dopamine in the periphery, and more Levodopa enters the CNS, thereby reducing the therapeutic dose of levodopa. Established that in the human body morphine stimulates specific receptors, which are called Physical Therapy receptors.